Fc Gamma Receptor CD64 Modulates the Inhibitory Activity of Infliximab
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چکیده
منابع مشابه
Fc Gamma Receptor CD64 Modulates the Inhibitory Activity of Infliximab
BACKGROUND Tumor necrosis factor (TNF) is an important cytokine in the pathogenesis of inflammatory bowel disease (IBD). Anti-TNF antibodies have been successfully implemented in IBD therapy, however their efficacies differ among IBD patients. Here we investigate the influence of CD64 Fc receptor on the inhibitory activity of anti-TNFs in cells of intestinal wall. METHODS Intestinal cell line...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0043361